N-(4-Bromobenzyl)carbamic acid tert-butyl ester

N-(4-Bromobenzyl)carbamic acid tert-butyl ester - Names and Identifiers

Name	tert-Butyl N-(4-bromobenzyl)carbamate
Synonyms	N-BOC-4-broMobenzylaMine 4-Bromo-N-BOC-benzylamine TERT-BUTYL 4-BROMOBENZYLCARBAMATE tert-Butyl N-(4-bromobenzyl)carbamate (4-BROMO-BENZYL)-CARBAMIC ACID TERT-BUTYL ESTER N-(4-Bromobenzyl)carbamic acid tert-butyl ester Carbamic acid, (4-bromophenyl)methyl-, 1,1-dimethylethyl ester Carbamic acid,N-[(4-bromophenyl)methyl]-, 1,1-dimethylethyl ester
CAS	68819-84-1
InChI	InChI=1S/C12H16BrNO2/c1-12(2,3)16-11(15)14-8-9-4-6-10(13)7-5-9/h4-7H,8H2,1-3H3,(H,14,15)

N-(4-Bromobenzyl)carbamic acid tert-butyl ester - Physico-chemical Properties

Molecular Formula	C12H16BrNO2
Molar Mass	286.16
Density	1.319±0.06 g/cm3(Predicted)
Melting Point	86-88℃
Boling Point	374.3±25.0 °C(Predicted)
Flash Point	177.8 °C
Water Solubility	at 25 deg C (mg/L): 6.688
pKa	12.05±0.46(Predicted)
Storage Condition	Sealed in dry,Room Temperature

N-(4-Bromobenzyl)carbamic acid tert-butyl ester - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	22 - Harmful if swallowed

N-(4-Bromobenzyl)carbamic acid tert-butyl ester - Upstream Downstream Industry

Downstream Products

tert-Butyl 4-ethynylbenzylcarbamate
(4-IODO-BENZYL)-CARBAMIC ACID TERT-BUTYL ESTER
[1-(4-BROMO-PHENYL)-ETHYL]-CARBAMIC ACID TERT-BUTYL ESTER
4-AMINOMETHYLPHENYLBORONIC ACID, PINACOL ESTER, HCL
(4-BROMO-BENZYL)-METHYL-CARBAMIC ACID TERT-BUTYL ESTER

N-(4-Bromobenzyl)carbamic acid tert-butyl ester - Introduction

tert-Butyl N-(4-bromobenzyl)carbamate is an organic compound with the chemical formula C13H18BrNO2. The following is an introduction to some of its properties, uses, formulation and safety information:

Nature:
tert-Butyl N-(4-bromobenzyl)carbamate is a colorless or pale yellow liquid. It is a hydrophobic compound that is soluble in organic solvents such as ethanol, methylene chloride and ether.

Use:
tert-Butyl N-(4-bromobenzyl)carbamate is commonly used as a reagent in organic synthesis. It can be used as a substrate or intermediate in a variety of organic reactions. One of its main uses is as an activator for the construction of heterocyclic compounds, but also for the synthesis of biologically active compounds.

Preparation Method:
The synthesis method of tert-Butyl N-(4-bromobenzyl)carbamate can be obtained by reacting N-(4-bromobenzyl) carbamic acid with tert-butyl chloroformate under appropriate conditions. This reaction generally needs to be carried out under an inert atmosphere.

Safety Information:
tert-Butyl N-(4-bromobenzyl)carbamate has limited safety information, it is necessary to follow relevant safety procedures when using and handling it. It may be irritating to the skin, eyes and respiratory tract, so wear appropriate protective equipment such as gloves, goggles and protective masks during operation. It should avoid contact with strong oxidants and strong acids to avoid dangerous reactions. During storage, it should be kept in a cool, dry, well-ventilated place, away from fire and ignition sources.

Last Update：2024-04-10 22:29:15